Reason 9.5 and later supports 64-bit VST2 (2.4) plugins
Reason 12.5 and later supports 64-bit VST3 and VST2 plugins
32-bit VST plugins are not supported.
VSTs that output MIDI are not supported in Reason.
Multitimbral VSTs (that can receive on separate MIDI channels) are not supported. You will then have to use one instance of the VST for each sound/channel.
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